Before receiving PADCEV, tell your healthcare provider about all
of your medical conditions, including if you:
If your healthcare provider prescribes PADCEV in combination with pembrolizumab for you, also read
the Medication Guide that comes with pembrolizumab for important information about pembrolizumab.
The most common side effects of PADCEV when used in combination with pembrolizumab include:
•
Changes in liver function and kidney function tests
•
Rash. See “What is the most important information I should know about PADCEV?”
•
Increased sugar (glucose) in the blood. See “High blood sugar (hyperglycemia)”
•
Numbness or tingling in your hands or feet. See “Nerve problems”
•
Increased lipase (a test done to check your pancreas)
•
Decreased white blood cell, red blood cell, and platelet counts
•
Tiredness
•
Decreased sodium, phosphate, and protein (albumin) in the blood
•
Itching
•
Diarrhea
•
Hair loss
•
Decreased weight
•
Decreased appetite
•
Increased uric acid in the blood
•
Increased or decreased potassium
•
Dry eye. See “Eye problems”
•
Nausea
•
Constipation
•
Change in sense of taste
•
Urinary tract infection
The most common side effects of PADCEV when used alone include:
•
Increased sugar (glucose) in the blood. See “High blood sugar (hyperglycemia)”
•
Changes in liver and kidney function tests
•
Decreased white blood cell, red blood cell, and platelet counts
•
Rash. See “What is the most important information I should know about PADCEV?”
•
Tiredness
•
Numbness or tingling in your hands or feet. See “Nerve problems”
•
Decreased protein (albumin), sodium, and phosphate in the blood
•
Hair loss
•
Decreased appetite
•
Diarrhea
•
Nausea
•
Itching
•
Increased uric acid in the blood
•
Dry eye. See “Eye problems”
•
Change in sense of taste
•
Constipation
•
Increased lipase (a blood test done to check your pancreas)
•
Decreased weight
•
Stomach (abdominal) pain
•
Dry skin
PADCEV may cause fertility problems in females and males, which may affect the ability to have children.
Talk to your healthcare provider if you have concerns about fertility.
These are not all the possible side effects of PADCEV.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.